Engineering Calcium Oxalate Crystal Formation in Arabidopsis
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چکیده
منابع مشابه
Protein-crystal Interactions in Calcium Oxalate Kidney Stone Formation
We have studied the ability of urinary molecules in altering the precipitation of kidney stone-related calcium oxalate monohydrate (COM) crystals and correlated the resulting morphologies with those of idiopathic COM kidney stones. We found that weakly acidic but highly glycosylated polyelectrolytes (Tamm Horsfall protein (THP), fetuinA, hyaluronic acid) do not significantly affect crystallizat...
متن کاملMagnesium reduces calcium oxalate crystal formation in human whole urine.
1. A low urinary magnesium was induced in normal volunteer subjects by giving cellulose phosphate; magnesium was added in vitro to yield urine samples of normal and high magnesium concentrations. 2. After rapid evaporation of these urine samples at pH 5.3 to standard osmolality the calcium oxalate crystals were measured by microscopy and isotopic methods. 3. There was a clear inverse correlatio...
متن کاملUrinary calcium oxalate crystal growth inhibitors.
Calcium stones occur because renal tubular fluid and urine are supersaturated with respect to calcium oxalate and phosphate. The process of stone formation includes crystal nucleation, growth, aggregation, and attachment to renal epithelia. Urine contains macromolecules that modify these processes and may protect against stone formation. Attention has focused especially on inhibitors of crystal...
متن کاملNormal calcium oxalate crystal growth inhibition in severe calcium oxalate nephrolithiasis.
Urine from mammalian kidneys is regularly supersaturated with respect to calcium oxalate monohydrate, the most common solid phase in human nephrolithiasis, and also inhibits the nucleation, growth, and aggregation of calcium oxalate crystals. Nephrolithiasis is often associated with increased supersaturation, and it is assumed that this increase overbalances the inhibition effects, causing ston...
متن کاملCrystal surface adhesion explains the pathological activity of calcium oxalate hydrates in kidney stone formation.
Renal tubular fluid in the distal nephron of the kidney is supersaturated with calcium oxalate (CaOx), which crystallizes in the tubules as either calcium oxalate monohydrate (COM) or calcium oxalate dihydrate (COD). Kidney stones are aggregates, most commonly containing microcrystals of COM as the primary inorganic constituent. Stones also contain small amounts of embedded proteins, which are ...
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ژورنال
عنوان ژورنال: Plant and Cell Physiology
سال: 2012
ISSN: 0032-0781,1471-9053
DOI: 10.1093/pcp/pcs071